Dominick DiNapoli, a good-natured but overweight man, struggles with his self-esteem and unhealthy eating habits. After his cousin's sudden death from a heart attack, which the family attributes to obesity, his sister Antoinette pressures him to seek help. Dominick visits a doctor who recommends a strict diet, but he finds it difficult to adhere to the regimen. Feeling isolated and desperate for companionship, Dominick joins a support group called "Chubby Checkers," where he meets other individuals with similar struggles and begins to find solace in their shared experiences.

As Dominick attempts to curb his overeating and make healthier choices, he faces numerous challenges and setbacks. His journey is compounded by the complexities of his personal relationships and the temptations that surround him daily. Despite these hurdles, he remains determined to turn his life around. The film sensitively and humorously explores themes of self-acceptance, the impact of family dynamics on personal growth, and the power of community support in overcoming personal battles.