Jamie Conway, a young fact-checker for a New York City magazine, spirals out of control following the death of his mother and the departure of his wife. Struggling with grief and loneliness, Jamie turns to alcohol and a party lifestyle, frequently indulging in nights full of drugs and empty social encounters. His best friend, Tad Allagash, encourages his wild behavior, leading Jamie into increasingly destructive situations. As Jamie's work performance deteriorates, he finds it difficult to hide his growing dependency on substances and the strain from those around him.

Balancing on the brink of losing his job and battling personal demons, Jamie is forced to confront the reality of his situation. A series of chaotic nights filled with desperate attempts to escape his pain pushes him towards a breaking point. The film portrays Jamie's journey through the nightlife of Manhattan, capturing the city's seductive allure and the harsh consequences of escapism. The narrative explores themes of addiction, personal loss, and the struggle for redemption, leaving Jamie to grapple with his choices and their impact on his future.