In the fictional French city of Ennui-sur-Blasé, an American magazine's European bureau prepares for publication its final issue after the sudden death of its beloved editor. The film unfolds through three distinct stories featured in this last edition, each encapsulating the unique essence of the magazine's commitment to world travel journalism. In the first story, a talented yet unstable artist, Moses Rosenthaler, is incarcerated for murder. His art captures the attention of art dealer Julian Cadazio, who recognizes its potential for commercial success. Despite Moses' refusal to leave prison, Cadazio embarks on a mission to secure his groundbreaking artwork for a major exhibition, showcasing the complex interplay between artistic integrity and commercial viability.

The second story highlights political intrigue and youthful rebellion as budding student activists, led by Zeffirelli and Juliette, rise against restrictions in a movement known as the Chessboard Revolution. The coverage comes from Lucinda Krementz, a dedicated journalist who negotiates the blurred lines between objective reporting and personal involvement. A third narrative involves a renowned food journalist, Roebuck Wright, who recounts his culinary adventure amidst a harrowing crime storyline. Each vignette vibrantly explores its thematic focus with flair and eccentricity, all reflecting on the human condition and journalistic dedication. The episodic structure captures the idiosyncratic nature of varied storytelling, serving as both a tribute to the magazine's legacy and an exploration of life's artistic and cultural complexities.