A group of celebrity friends gather at James Franco's house for a star-studded party. Among the attendees are Seth Rogen, Jay Baruchel, Jonah Hill, Craig Robinson, and many other famous faces, playing exaggerated versions of themselves. During the raucous festivities, strange events begin unfolding in Los Angeles—tremors shake the earth, and a mysterious, blue light beams down from the sky, sucking people into the heavens. Chaos ensues as the partygoers grapple with the reality that this may be the beginning of an apocalyptic event.

As the city descends into madness, the core group of friends finds themselves barricaded inside Franco's home, cut off from the outside world. With diminishing supplies and increasing tension, they struggle to survive while attempting to understand the bizarre and catastrophic events happening outside. As they face their personal demons and the strain on their friendships, they realize that survival will require more than just hoarding resources—it will require facing the horrors that lie ahead and the uncertainties of their fate.