Danny Fisher, a troubled young man with a natural gift for singing, struggles to make ends meet while living in the French Quarter of New Orleans. After failing to graduate from high school for a second time, Danny takes on various odd jobs to support his family. When he lands a gig performing at a local nightclub, his talent quickly catches the eye of both Maxie Fields, a powerful and unscrupulous gangster, and Nellie, a kind-hearted but world-weary singer. Maxie sees potential in Danny as a headliner for his clubs, while Nellie takes a personal interest in helping him find his way.

As Danny's career begins to take off, he finds himself torn between the lure of Maxie's influence and the desire to lead an honest life. His involvement with Maxie's gang deepens, drawing him into increasingly dangerous situations and straining his relationships with those he loves, including his aspiring dancer sister and patient but disappointed father. Danny's path is further complicated by his growing feelings for Nellie, as well as for Ronnie, Maxie’s unstable but alluring mistress. These entanglements force Danny to confront difficult decisions about his future and the kind of man he wants to become, setting the stage for a dramatic series of events that will determine his fate.