A young American woman named Nora arrives in Rome and unexpectedly witnesses a brutal murder in her hotel room. Shocked and disoriented, she reports the crime but the police dismiss her claims due to a lack of evidence. Determined to uncover the truth, Nora discovers a connection between the murder she saw and a series of unsolved killings targeting young women. As she delves deeper into the mystery, she becomes entangled with various suspicious characters, including a charming writer named Marcello and a secretive artist with a penchant for violent classic literature.

As the tension mounts, Nora's sense of paranoia intensifies; sinister events follow her every move. She uncovers clues that seem to point to an ancient curse and a deranged serial killer. Her relentless pursuit for answers puts her in grave danger, making it increasingly difficult to distinguish between friend and foe. Time is running out, forcing Nora to confront the terrifying truth hidden within the labyrinthine streets of Rome.