In the early 1980s, a gay activist and a doctor form an alliance as they begin to uncover the emerging AIDS crisis hitting New York City's gay community. Facing societal indifference and government neglect, they work to raise awareness about the epidemic that is claiming an increasing number of lives in their community. Their efforts are met with resistance, not only from the outside world but also from within the gay community, some of whom fear that public acknowledgment of the crisis will incite further homophobia and discrimination.

As the activist becomes more involved, his personal and professional relationships are put to the test. He battles against a lack of funding, bureaucratic hurdles, and the widespread stigma associated with the disease. Amidst the crisis, the activist's relationships with his friends and his partner undergo severe strain, highlighting the personal toll of the epidemic. The narrative captures the fear, anger, and desperation of a community fighting for its very survival, while also exploring themes of love, activism, and the struggle for acceptance.