Frank and Lenore Davis eagerly anticipate the birth of their second child, but their joy quickly turns to horror when the baby is born as a monstrous, mutant killer. The infant viciously slaughters everyone in the delivery room before escaping into Los Angeles. The Davis family is left in a state of shock and confusion, grappling with the reality of their child's inhuman nature. The authorities launch a manhunt, while Frank struggles with the shame and guilt associated with their newborn, and Lenore falls into a state of denial, convinced that their baby deserves love despite its murderous tendencies.

As the killings continue, the monstrous infant manages to evade police, causing widespread panic. The media frenzy escalates, putting immense pressure on Frank. Amidst the chaos, Frank uncovers disturbing secrets about experiments and genetic anomalies that point to the cause of the mutation. As he delves deeper, he finds himself confronting unethical decisions and struggling with moral dilemmas about parenthood and societal responsibility. With tensions running high, Frank must decide between loyalty to his family and the safety of the public, while Lenore becomes increasingly consumed by maternal instincts toward their now notorious offspring.