A group of friends decides to embark on an extravagant vacation getaway to an exotic island. They are eager to enjoy their luxurious surroundings, and during a night out, they meet a mysterious nightclub owner who introduces them to a new designer drug that intensifies the user's desires and sensations. He emphasizes that the drug should only be taken once in a lifetime. Intrigued and eager to push their boundaries, the friends decide to experiment with it. Initially, they experience heightened euphoria and liberation, feeling more alive and connected than ever before. The island's atmosphere seemingly amplifies their experiences, leading to an unforgettable night.

As the effects of the drug begin to fade, some members of the group can't resist the temptation to take it again despite the warnings. This decision sets off a dangerous chain of events, causing their darkest impulses to surface uncontrollably. Suspicion and paranoia start to take hold as the group's bonds are tested. With each passing moment, they become more entwined in a web of chaos and violence, struggling to maintain their sanity in the face of their uncontrollable urges. Their idyllic vacation turns into a nightmarish struggle for survival against both the external threats of the island and their inner demons.