In the late 19th century, Lawrence Talbot, a renowned Shakespearean actor, returns to his family's estate in Blackmoor upon learning of his brother Ben's mysterious disappearance. Raised by his estranged father, Sir John Talbot, Lawrence is determined to find his brother, especially after meeting Gwen Conliffe, Ben's fiancée. The local populace whispers of a beast roaming the moors, responsible for a series of grisly killings. As the full moon rises, Lawrence uncovers dark family secrets while searching for answers, leading him to a Gypsy camp. Amidst escalating tensions among the villagers, Lawrence experiences a terrifying encounter with the elusive creature that leaves him cursed and haunted.

Lawrence grapples with emerging monstrous instincts as the full moon brings uncontrollable changes. Inspector Francis Aberline from Scotland Yard arrives in Blackmoor, suspecting Lawrence in the brutal murders. Struggling with his transformations and hunted by both the police and his inner demons, Lawrence faces an agonizing battle against the primal force consuming him and the foreboding familial legacy lurking within Blackmoor. Torn between his humanity and the monstrous instincts awakened by the curse, he must decipher truths hidden in shadows to stop the violence ravaging his home and save Gwen and himself from impending doom. As conflicts collide, Lawrence is driven to confront the ominous mysteries surrounding the beast that threatens all he holds dear.