In the late 15th century, a determined Genoese navigator believes he can find a westward route to the East Indies, thereby bypassing the established and perilous land routes. He petitions for support from various European monarchs, ultimately gaining favor from the Spanish Crown. With backing from Queen Isabella, he sets sail across uncharted waters on an audacious voyage, driven by his conviction and dreams of wealth. As he and his crew endure the fears and difficulties of their journey, they finally reach a new land, encountering indigenous people and claiming the territory for Spain.

Upon their return to Europe, the navigator's initial voyage sparks both excitement and controversy. He organizes a subsequent expedition, this time with more settlers and resources, aiming to establish a lasting colony. However, the endeavor soon faces numerous challenges, including resistance from the native population, internal dissent among the settlers, and personal rivalries. As the situation grows increasingly complex, he finds his vision for a new world tested by greed, betrayal, and the harsh realities of colonization.