Two Chicago police officers, Ray Hughes and Danny Costanzo, are veteran detectives well-known for their maverick ways and their ability to take down tough criminals. After narrowly escaping death during a particularly harrowing pursuit of a notorious drug lord, they begin to reassess their lives and careers. Shaken by the close call, the partners seriously contemplate retirement, envisioning a less risky future where they can enjoy the pleasantries of life without the shadow of danger hanging over them. With dreams of swapping their badges for a sunnier existence away from the gritty streets of Chicago, they decide to retire to sunny Key West and open a bar, envisioning a carefree life ahead.

However, before transitioning to their sought-after peaceful life, the duo is tasked with a high-stakes operation, running against the clock to nab an infamous drug kingpin who has been eluding the law. Determined to end their police careers on a high note, they throw themselves into the case with their usual blend of humor and grit. Their pursuit leads them deep into the treacherous underworld of sophisticated criminals, testing their expertise and the strength of their friendship. As the investigation progresses, it becomes a frantic race that takes them from the city's freezing streets to its luxurious, high-powered social circles, amplifying the very risks they hoped to leave behind.