Carol White, a suburban housewife in the 1980s living in the San Fernando Valley, leads a seemingly perfect life with her husband and stepson. However, she gradually begins experiencing mysterious symptoms such as headaches, nosebleeds, and fatigue. Puzzled by her deteriorating health, Carol consults various doctors but receives no clear diagnosis. Her physical condition grows worse, and she becomes increasingly sensitive to everyday chemicals and pollutants. Her life begins to unravel as she struggles with these inexplicable health issues, leading to rising anxiety and isolation.

As her condition worsens and conventional medical advice fails her, Carol turns to alternative therapies and finds solace in a New Age treatment center called Wrenwood. The center promotes a philosophy of healing through self-examination and lifestyle changes. Here, she meets other individuals suffering from similar conditions, providing her a sense of community. The narrative explores Carol's journey as she grapples with her illness, societal disconnect, and the search for an elusive sense of safety and well-being.