Medical student Dan Cain becomes involved in a bizarre experiment with his new roommate, Herbert West, a qualified scientist who has just transferred to Miskatonic University. West is obsessed with overcoming death and has developed a serum that can reanimate deceased tissue. Despite his initial skepticism and ethical concerns, Dan is eventually persuaded to assist West in his experiments, driven by both a fascination with the scientific potential and a desire to help his fiancée, Megan. Their first successful reanimation of a dead cat raises ethical alarms and foreshadows the horrific consequences of tampering with nature.

As the experiments escalate, West and Dan's activities attract the suspicion of Dr. Carl Hill, a colleague who becomes obsessed with West's groundbreaking research. Hill's undisclosed ambitions and the college's protocols lead to increasingly dangerous and grotesque scenarios. These events spiral out of control, dragging the characters into a nightmarish realm where the boundaries between life and death are irreversibly blurred. Despite their noble intentions, the horrific repercussions of their work begin to take a devastating toll, leading to an intensifying series of conflicts and grotesque revelations. The characters’ desperate attempts to manage the chaos leave a trail of unintended and macabre outcomes.