Kathleen Conklin, a philosophy graduate student in New York City, finds herself thrust into the dark and mysterious world of vampirism after being bitten by a seductive woman named Casanova. As her body undergoes drastic changes, Kathleen wrestles with an intense and insatiable craving for human blood, which leads her to question her own moral and philosophical beliefs. Her initial resistance collapses in the face of overwhelming hunger, and she starts to feed on strangers to satiate her newfound addiction. Her quest for answers deepens as she encounters various individuals who are either interested in or affected by vampirism.

As Kathleen's addiction intensifies, she dives deeper into philosophical and existential questions about human nature, sin, and redemption. Her journey leads her to a reclusive vampire named Peina, who has managed to suppress his own cravings temporarily. Peina offers insights into their shared affliction, exploring themes of disease, free will, and the essence of evil. As her hunger escalates, Kathleen's academic and personal life begin to crumble, forcing her to confront the ultimate questions about her identity and humanity. Her transformation becomes a powerful metaphor for issues like addiction and alienation in modern society.