In a comedic twist on the classic vampire tale, a naive solicitor named Thomas Renfield travels to Transylvania on business to meet with Count Dracula, who plans to buy real estate in England. Upon arrival at the Count's eerie castle, Renfield quickly falls under Dracula's spell and becomes his devoted servant. The clueless Renfield helps Dracula make his way to England, where the Count takes up residence in Carfax Abbey. Renfield is soon institutionalized for his increasingly bizarre behavior, a side effect of Dracula's influence. Meanwhile, Dracula infiltrates the social circle of Dr. Seward, whose insane asylum Renfield is held in. Seward's beautiful daughter Mina is drawn to the enigmatic and mysterious Dracula, who has dark and nefarious designs.

As Dracula sets his sights on Mina and her friend Lucy, strange phenomena begin to occur, raising the suspicion of those around them. Abraham Van Helsing, an expert on vampires, is called in to consult on Lucy's peculiar illness after several mysterious nocturnal visits from Dracula leave her weakened. Joining forces with Jonathan Harker and Dr. Seward, Van Helsing sets out to uncover the truth about the Count and protect Mina and Lucy from his perilous grasp. Using humor and satire, the story weaves through the traditional gothic narrative with absurdity as well as slapstick moments, leading to a confrontation between Van Helsing's team and the sanguinary Count that will determine the fates of all involved.