Ethan Hunt, retired from active duty and engaged to be married, is leading a quiet life training new IMF agents and planning a life with his fiancée, Julia. His peaceful existence is shattered when an IMF agent is captured while tracking the elusive arms dealer, Owen Davian. Under pressure, Hunt is compelled to return to the field to rescue the agent and confront the brutal and dangerous Davian.

Hunt assembles a team of trusted allies and undertakes a daring rescue operation that leads to a high-stakes mission to stop Davian from obtaining a dangerous object known as the "Rabbit's Foot." The mission takes them across the globe, from Berlin to the Vatican, where they must infiltrate secure locations and face off against Davian's well-equipped and relentless henchmen.