In the Valley of Peace, Po is now living his dream as the Dragon Warrior, protecting it alongside his friends and fellow kung fu masters, the Furious Five. However, Po's new life is threatened by the emergence of a formidable villain, Lord Shen, who has a powerful weapon that challenges the very existence of kung fu itself. Shen's connection to Po's past propels the panda on a quest across China to confront this threat and unlock the secrets of his mysterious origins.

Along the journey, Po and the Furious Five confront various challenges that not only test their physical strength but also their emotional bonds. The group's loyalty, courage, and friendships are put to the test as they face this new adversary. Meanwhile, Po struggles with flashbacks of his past, which are somehow connected to Lord Shen's weapon. As they venture deeper into enemy territory, Po must find a way to unlock his true potential and find inner peace, which he realizes is the key to defeating Shen and preserving kung fu.