Peter Highman, an uptight architect, is desperate to return to Los Angeles in time for the birth of his first child. However, his plans go awry when he encounters Ethan Tremblay, an aspiring actor with eccentric behavior. After a series of unfortunate events at the airport, Peter ends up being put on the "no-fly" list, losing his wallet and luggage in the process. With no other option and time running out, Peter reluctantly agrees to a cross-country road trip with Ethan, who is also traveling to Los Angeles. Their journey quickly becomes fraught with disasters, ranging from car troubles to run-ins with law enforcement, all exacerbated by Ethan's bizarre antics and Peter's frayed nerves.

As they traverse various states, the mismatched duo confronts a multitude of obstacles that test Peter’s patience and Ethan’s optimistic outlook. Their tenuous relationship is further strained by misunderstandings and personality clashes, but they also experience moments of unexpected bonding and revelations. Through a series of misadventures that include encounters with eccentric characters, physical mishaps, and ethical dilemmas, both men are forced to re-evaluate their lives and priorities. Eventually, their chaotic trip reveals underlying truths about friendship, responsibility, and personal growth.