A young supermarket cashier named Ronna finds herself in a desperate financial situation and agrees to participate in a quick drug deal to make some fast cash. Things spiral out of control when she decides to double-cross the dealer and sell the drugs herself at a rave. As the night progresses, Ronna's plan goes awry, leading to a series of chaotic and dangerous events involving eccentric characters and unforeseen circumstances. Her friends Claire and Mannie become unwilling accomplices, and the trio's reckless decisions lead them deeper into a world of peril, forcing them to navigate treacherous encounters.

Meanwhile, Simon, Ronna's British co-worker, embarks on his own adventure to Las Vegas with his friends. They find themselves caught up in a wild escapade involving stolen cars, strip clubs, and gun-toting thugs. Concurrently, actors Adam and Zack, who attempt to buy drugs from Ronna, face their own troubles with the law and a suspiciously friendly police officer. Throughout these intersecting storylines, the characters' choices intertwine with disastrous and humorous consequences, ultimately culminating in a tension-filled resolution as the night reaches its climax. The film weaves these separate yet interconnected stories together, exploring themes of chance, irresponsibility, and the unexpected repercussions of seemingly minor decisions.