In the year 2176, Mars has been colonized by Earth, but the red planet is far from tamed. A matriarchal society oversees the colonies, and resources are mined from the Martian soil to supply the needs of the distant Earth. The story centers on a police officer, Melanie Ballard, who is part of a team assigned to transfer a dangerous prisoner, Desolation Williams, back to the main administrative Martian city. As Ballard and her team arrive in the mining town where Williams is held, they find it eerily deserted. The mystery deepens when they discover the inhabitants have fallen victim to a malevolent force.

Unbeknownst to the team, they have stumbled upon an ancient Martian civilization's secret—a horrifying force unleashed from a sealed away mining site. This sinister entity possesses the bodies of the miners, turning them into violent, mindless hosts bent on death and destruction. As night falls, Ballard, Williams, and the surviving members of the squad must band together to fend off the possessed miners. Trapped in the remote outpost, with communication lines cut and transportation destroyed, they prepare for a relentless battle for survival against the unearthly terror that has awakened on the planet's surface, challenging their notions of enemy and ally alike.