In a world where the Easter Bunny is a revered figure, a young rabbit named E.B. is next in line to inherit the title from his father. However, E.B. dreams of becoming a famous drummer instead of taking over the family tradition. Disobeying his father, he escapes to Hollywood to pursue his passion, leaving the Easter Bunny's complex responsibilities in jeopardy. Meanwhile, Fred O'Hare, an unemployed human struggling to find his purpose, accidentally hits E.B. with his car. E.B. then convinces Fred to provide him with shelter while he continues his quest for musical stardom.

As E.B. chases his dreams, chaos ensues at the Easter Island factory where the preparations for Easter are in full swing. Without E.B.'s leadership, the factory faces several disruptions, and an ambitious chick named Carlos plots to take over the Easter Bunny's role. Fred and E.B. form an unlikely friendship and face significant challenges together. Both must confront their individual insecurities and responsibilities while navigating a series of comedic and heartfelt situations that will ultimately shape their future and the fate of Easter.