High school graduate Scott Thomas is dumped by his girlfriend at his graduation, leading to an emotional upheaval as he faces an uncertain future. His world is further turned upside down when he discovers that his German pen pal, Mieke, whom he's always thought was a male due to the name's masculine interpretation in the United States, is actually a beautiful girl. After a series of misunderstandings involving a raunchy email, Scott realizes he has feelings for Mieke, but his mistake causes her to block all communication with him. Feeling that he must make things right and confront his feelings for Mieke, Scott impulsively decides to travel to Europe with his friends to find her and express his true emotions.

Scott is joined by his best friend, Cooper, and twins Jenny and Jamie, as they embark on a raucous European adventure. The group experiences the classic backpacking trip filled with mishaps, misunderstandings, and misadventures as they navigate foreign cultures and customs. From London to Paris, each city presents a new set of challenges and comedic situations, including encounters with aggressive soccer hooligans, awkward moments at a nude beach, and a chaotic visit to an Amsterdam club. Through it all, the friends meet a collection of quirky characters that help or hinder their journey as they trek across the continent in search of Mieke, with Scott hoping to gain both her forgiveness and her heart.