In swinging 1960s London, a young, attractive man named Alfie Elkins leads a life steeped in casual affairs and fleeting relationships. A smooth-talking chauffeur with an abundance of charm, he considers himself a ladies' man, moving from woman to woman with a self-absorbed detachment and a refusal to commit. His conquests provide him with emotional and physical pleasure without the need for genuine emotional connections. Preferring not to concern himself with the consequences of his actions, Alfie treats his relationships as escapades that feed his vanity and hedonistic desires.

As Alfie’s story unfolds, the consequences of his selfish behavior begin to surface. He navigates through various liaisons with women, ranging from a single mother to a middle-aged married woman, leaving a trail of emotional turmoil in his wake. His personal philosophy is tested and his attitude towards relationships is challenged through his interactions with these women. However, despite the negative impact of his lifestyle, Alfie remains aloof to the moral complexities of his actions, grappling only superficially with the potential repercussions of his incessant need for self-gratification. This lifestyle, driven by a compulsive avoidance of personal responsibility, starts to glimmer with the possibility of transformation as Alfie encounters situations that challenge his views on life and love.