When a prisoner transport plane crashes, Mark Sheridan, one of the surviving prisoners, escapes amidst the chaos. Unbeknownst to him, he's being relentlessly pursued by U.S. Marshal Samuel Gerard and his team. Sheridan is a former government operative who has been falsely accused of murder. As he tries to evade capture and simultaneously prove his innocence, Gerard and his team employ every resource to track him down, believing him to be a dangerous fugitive.

Gerard’s investigation uncovers that Sheridan's case is far more complicated and potentially involves corrupt elements within the government. Alongside his skilled but sometimes insubordinate deputy, John Royce, Gerard traverses various states uncovering layers of deceit while dealing with internal conflicts and uncertainties within his team. The chase tests their limits and moralities, blurring the lines between what is lawful and what is just as they race against time to bring the right man to justice.