White Mike is a privileged young man who has chosen to drop out of his posh New York private school to become a drug dealer for his affluent classmates. Although once wealthy, his life took a dark turn after his mother's untimely death. White Mike's main product is marijuana, but he learns about a new, dangerous designer drug known as "Twelve," distributed by his cousin, Charlie. As he navigates the highs and lows of the lucrative yet perilous world of drug dealing, his childhood friend Hunter finds himself falsely accused of murder, adding more tension to White Mike's already complicated life.

Meanwhile, various characters from the Upper East Side are entangled in their own struggles, exacerbating the turmoil. The beautiful but troubled Molly is secretly in love with White Mike, while other privileged teens like Jess experiment with "Twelve," leading to catastrophic consequences. Relationships fray, and lives spiral out of control, culminating in a dramatic party that brings the intersecting lives to a head. As the events unfold, the boundaries between the privileged and the desperate blur, exposing the raw underbelly of a seemingly perfect world.