A brilliant yet unhinged scientist develops a serum that allows him to become invisible. Obsessed with his high school crush who never reciprocated his feelings, he aims to perfect the serum to use it to his advantage and to finally make an impact. However, his experiments are fraught with mishaps, causing him to lose a prestigious teaching position. He then falsifies his credentials to secure a new job at a high school, hoping for a fresh start and an opportunity to further his research in secrecy.

As he settles into his new role, the scientist becomes a laughing stock among his students due to his awkward mannerisms and outdated teaching methods. Despite this, his obsession grows, and he eventually completes his invisibility serum. The power of being unseen becomes an intoxicating force, heightening his deepest desires and dark inclinations. With his new-found ability, he embarks on a spree of voyeuristic and revenge-fueled endeavors, targeting those he feels have wronged him, particularly the female students and staff members who he believes have slighted him. This sets off a chain of events that spirals rapidly out of control, with dire consequences for both him and those around him.