James Bond, working again for MI6 after a period of reactivation, is sent to a health clinic for rest and recuperation. During his stay, he uncovers an illegal operation, involving the theft of two nuclear warheads by a member of the terrorist organization, SPECTRE. The mastermind behind the plot is Maximillian Largo, a wealthy and influential man who plans to hold the world to ransom. Bond follows the leads to the Bahamas, where he encounters Domino Petachi, Largo's mistress, who is unaware of her boyfriend's criminal activities. Bond begins to work on winning her trust to gain more information about Largo's plans.

As Bond delves deeper, he crosses paths with various operatives and faces several dangerous encounters, consistently staying one step ahead of his adversaries. His investigation takes him across various locations, where he skillfully uncovers clues that point to the looming threat of a nuclear disaster. Partnering with Domino, who becomes aware of Largo's true nature, Bond fights against time to stop the catastrophic scheme orchestrated by SPECTRE. The high-stakes pursuit leads to a series of intense confrontations, each bringing Bond closer to unmasking and thwarting the villainous plot.