In the summer of 1990, paleontologist Peter Larson and his team from the Black Hills Institute discover the largest, most complete Tyrannosaurus rex fossil ever found, which they name "Sue" after the woman who first spotted the bones. The initial excitement and scientific promise of Sue's discovery quickly spiral into controversy when ownership of the fossil becomes contested. Several parties, including the United States government, Native American tribes, and landowners, lay claim to Sue, leading to an intense legal battle. This turmoil disrupts what could have been a groundbreaking addition to our understanding of prehistoric life.

Caught in a web of complex legal issues, Peter Larson and his team face harsh accusations that put both their reputations and freedoms at risk. As they navigate courtroom struggles and media scrutiny, the situation not only jeopardizes the future of Sue but also the very existence of the Black Hills Institute. Amid these challenges, the team’s unwavering commitment to preserving Sue for scientific study underscores the tension between scientific progress and legal constraints. The film captures their emotional journey and quest to reclaim Sue, illustrating the high stakes and sacrifices involved in the world of paleontology.