Claus von Bülow, a wealthy and enigmatic socialite, is accused of attempting to murder his wife, Sunny, by inducing a coma through insulin injections. Sunny, now vegetative, once lived a glamorous life but was plagued by personal demons that led to deteriorating health and issues within their marriage. Claus's defense appears grim until he hires Harvard law professor Alan Dershowitz to overturn his conviction. Dershowitz, driven by a mix of academic curiosity and belief in due process, assembles a team of students to scrutinize the evidence and find inconsistencies in the prosecution's case.

As they dive deeper, the team uncovers a complex web of familial discord, financial desperation, and dubious medical practices. Claus's aloof demeanor and questionable morals make him a challenging client, yet Dershowitz remains intent on uncovering the truth. The investigation reveals both new doubts about Claus's guilt and troubling insights into Sunny's own life choices. As they prepare for the appeals court, tactics on both sides expose the intricate dance between wealth, power, and justice.