Carol Anne Freeling is sent to live with her aunt and uncle in a modern high-rise building in Chicago, where she hopes to escape the malevolent supernatural forces that have plagued her family. The skyscraper's reflective surfaces become conduits for the ghostly presence that has followed her. Dr. Seaton, a skeptical psychiatrist, believes that Carol Anne's experiences are fabrications stemming from trauma. However, her aunt Pat and uncle Bruce soon witness unexplainable phenomena, realizing that something truly sinister is at work.

As strange occurrences escalate, the building's advanced technologies and mirrored walls turn against its residents. Carol Anne's psychic abilities attract the vengeful spirit of Reverend Kane, who uses the building’s architecture to isolate and terrorize them. The experiences grow increasingly dangerous and surreal, causing desperation to mount as the family attempts to rescue Carol Anne from Kane's grasp.