Five childhood friends reunite after 20 years to attempt an epic pub crawl they failed to complete in their youth. Gary King, the ringleader, is a middle-aged man still clutching at the memories of his adolescent glory days. In a bid to recapture their past, he convinces the now reluctant and distant group, which includes the responsible Andy, the meek Oliver, the laid-back Steven, and the dependable Peter, to retrace their steps through their hometown of Newton Haven and finally reach the fabled final pub, The World’s End. The challenge: to down a pint at each of the town's 12 pubs in a single night.

As the friends make their way from pub to pub, they begin to notice that the townspeople are acting unusually. They're greeted with strange behavior and an eerie sense of conformity among the residents. With each pint, the reality of their situation becomes more apparent and bizarre, hinting that there's much more at stake than just a night of drunken revelry. The group's resolve is tested as they confront the changes in their friendships, their lives, and perhaps, the very fate of humanity itself, all while trying to reach the cherished last stop on their list.